The most recent contribution advancing knowledge in this area is a study entitled "Integrative analysis of mRNA and miRNA expression profiles and somatic variants in oxysterol signaling in early-stage luminal breast cancer", recently published in Molecular Oncology (Wiley, IF=6.6, Q1). The study combines data on expression and somatic mutation of 113 genes that have been shown or predicted to interact with oxysterols with expression data of the entire miRNA transcriptome, and maps their interrelationships as well as their impact on disease prognosis and other clinical factors.
Holy P.; Brynychova V.; Seborova K.; Hanicinec V.; Kozevnikovova R.; Trnkova M.; Vrana D.; Gatek J.; Kopeckova K.; Mrhalova M.; Soucek P.: Integrative analysis of mRNA and miRNA expression profiles and somatic variants in oxysterol signaling in early-stage luminal breast cancer. Mol Oncol. 2023 Jul 25. doi: 10.1002/1878-0261.13495.
