Publications 2021

Machuldova, A., Houdova, L., Kratochvilova, K., Leba, M., Jindra, P., Ostasov, P., Maceckova, D., Klieber, R., Gmucova, H., Sramek, J., & Holubova, M. (2021). Single-Nucleotide Polymorphisms in MICA and MICB Genes Could Play a Role in the Outcome in AML Patients after HSCT. Journal of clinical medicine, 10(20), 4636.

Lysak, D., Brychtová, M., Leba, M., Čedíková, M., Georgiev, D., Jindra, P., Vlas, T., & Holubova, M. (2021). Long-Term Cryopreservation Does Not Affect Quality of Peripheral Blood Stem Cell Grafts: A Comparative Study of Native, Short-Term and Long-Term Cryopreserved Haematopoietic Stem Cells. Cell transplantation, 30, 9636897211036004.

Machuldova A, Holubova M, Caputo VS, Cedikova M, Jindra P, Houdova L and Pitule P (2021) Role of Polymorphisms of NKG2D Receptor and Its Ligands in Acute Myeloid Leukemia and Human Stem Cell Transplantation. Front. Immunol. 12:651751.

Fiala, O., Ostašov, P., Rozsypalová, A., Hora, M., Šorejs, O., Šustr, J., Bendová, B., Trávníček, I., Filipovský, J., Fínek, J., & Büchler, T. (2021). Metformin Use and the Outcome of Metastatic Renal Cell Carcinoma Treated with Sunitinib or Pazopanib. Cancer management and research, 13, 4077–4086.

Navvabi, N., Kolikova, P., Hosek, P., Zitricky, F., Navvabi, A., Vycital, O., Bruha, J., Palek, R., Rosendorf, J., Liska, V., & Pitule, P. (2021). Altered Expression of MBNL Family of Alternative Splicing Factors in Colorectal Cancer. Cancer genomics & proteomics, 18(3), 295–306.

Hlaváč, V., Václavíková, R., Brynychová, V., Ostašov P., Koževnikovová, R., Kopečková, K., Vrána, D., Gatěk, J., & Souček, P. (2021). Role of Genetic Variation in Cytochromes P450 in Breast Cancer Prognosis and Therapy Response. International journal of molecular sciences, 22(6), 2826.

Rakova, J., Truxova, I., Holicek, P., Salek, C., Hensler, M., Kasikova, L., Pasulka, J., Holubova, M., Kovar, M., Lysak, D., Kline, J. P., Racil, Z., Galluzzi, L., Spisek, R., & Fucikova, J. (2021). TIM-3 levels correlate with enhanced NK cell cytotoxicity and improved clinical outcome in AML patients. Oncoimmunology, 10(1), 1889822.

Ulrychová, L., Ostašov, P., Chanová, M., Mareš, M., Horn, M., & Dvořák, J. (2021). Spatial expression pattern of serine proteases in the blood fluke Schistosoma mansoni determined by fluorescence RNA in situ hybridization. Parasites & vectors, 14(1), 274.

Publications 2020

Fiala, O., Sorejs, O., Hosek, P., Liska, V., Vycital, O., Bruha, J., Kucera, R., Topolcan, O., Finek, J., Maceckova, D., & Pitule, P. (2020). Association of miR-125b, miR-17 and let-7c Dysregulations With Response to Anti-epidermal Growth Factor Receptor Monoclonal Antibodies in Patients With Metastatic Colorectal Cancer. Cancer genomics & proteomics, 17(5), 605–613.

Ostasov P., Robertson, H., Piazza, P., Datta, A., Apperley, J., Houdova, L., Lysak, D., Holubova, M., Tesarova, K., Caputo, V. S., & Barozzi, I. (2020). Evolution of Advanced Chronic Lymphoid Leukemia Unveiled by Single-Cell Transcriptomics: A Case Report. Frontiers in oncology, 10, 584607.

Ostasov, P., Tuma, J., Pitule, P., Moravec, J., Houdek, Z., Vozeh, F., Kralickova, M., Cendelin, J., & Babuska, V. (2020). Sonic Hedgehog and Triiodothyronine Pathway Interact in Mouse Embryonic Neural Stem Cells. International journal of molecular sciences, 21(10), 3672.

Tichanek, F., Salomova, M., Jedlicka, J., Kuncova, J., Pitule P., Macanova, T., Petrankova, Z., Tuma, Z., & Cendelin, J. (2020). Hippocampal mitochondrial dysfunction and psychiatric-relevant behavioral deficits in spinocerebellar ataxia 1 mouse model. Scientific reports, 10(1), 5418.

Dekojová, T., Houdová, L., Fatka, J., Pitule, P., Ostašov, P., Caputo, V. S., Gmucová, H., Lysák, D., Jindra, P., & Holubová, M. (2020). Dynamic Changes of Inhibitory Killer-Immunoglobulin-Like Receptors on NK Cells after Allogeneic Hematopoietic Stem Cell Transplantation: An Initial Study. Journal of clinical medicine, 9(11), 3502.

Kolenčík, D., Shishido, S. N., Pitule, P., Mason, J., Hicks, J., & Kuhn, P. (2020). Liquid Biopsy in Colorectal Carcinoma: Clinical Applications and Challenges. Cancers, 12(6), 1376.

Holicek, P., Truxova, I., Kasikova, L., Vosahlikova, S., Salek, C., Rakova, J., Holubova, M., Lysak, D., Cremer, I., Spisek, R., and Fucikova, J. (2020). Assessment of NK cell-mediated cytotoxicity by flow cytometry after rapid, high-yield isolation from peripheral blood. Methods in enzymology, 631, 277–287.

Publications 2019

Vycital O, Pitule P, Hosek P, Kriz T, Treska V, Liska V. Expression of Serpin B9 as a Prognostic Factor of Colorectal Cancer. Anticancer Res. 2019 Nov;39(11):6063-6066. doi: 10.21873/anticanres.13813

Fiala O, Ostasov P, Hosek P, Sorejs O, Liska V, Buchler T, Poprach A, Kucera R, Topolcan O, Sustr J, Sedivcova M, Finek J. The Predictive Role of Primary Tumour Sidedness in Metastatic Colorectal Cancer Treated With Targeted Agents. Anticancer Res. 2019 Oct;39(10):5645-5652. doi: 10.21873/anticanres.13761

Truxova I, Kasikova L, Salek C Hensler M, Lysak D, Holicek P, Bilkova P, Holubova M,……. Spisek R, Fucikova J. Calreticulin exposure on malignant blasts correlates with improved natural killer cell-mediated cytotoxicity in acute myeloid leukemia patients. Haematologica. 2019 Oct 3. pii: haematol.2019.223933. doi: 10.3324/haematol.2019.223933

Benjamin M. Tang, Maryam Shojaei, …….., Marek Nalos, Monika Holubova, Tracy Chew, David Booth, Anand Kumar, Anthony McLean & Klaus Schughart. Neutrophils-related host factors associated with severe disease and fatality in patients with influenza infection. Nature Communications,10, Article number: 3422 (2019) , DOI: 10.1038/s41467-019-11249-y

Holubova M, Leba M, Gmucova H, Caputo V, Jindra P and Lysak D. Improving the Clinical application of natural killer cells by modulating signals signal from target cells. Int. J. Mol. Sci. 2019, 20, 3472; doi:10.3390/ijms20143472

P.Holicek, I.Truxova, L.Kasikova, S.Vosahlikova, C.Salek, J.Rakova, M.Holubova, D.Lysak, I.Cremer, R.Spiseka, J.Fucikova. assessment of NK cell-mediated cytotoxicity by flow cytometry after rapid, high-yield isolation from peripheral blood. Methods in Enzymology. June 2019,

Thiele JA, Pitule P, Hicks J, Kuhn P. Single-cell analysis of circulating tumor cells. Methods Mol Biol. 2019;1908:243-264. doi: 10.1007/978-1-4939-9004-7_17

Altanerova U, Jakubechova J, Benejova K, Priscakova P, Pesta M, Pitule P, Topolcan O, Kausitz J, Zduriencikova M, Repiska V, Altaner C. Prodrug suicide gene therapy for cancer targeted intracellular by mesenchymal stem cell exosomes. Int J Cancer. 2019 Feb 15;144(4):897-908. doi: 10.1002/ijc.31792

Publications 2018

Miklíková M, Jarkovská D, Čedíková M, Švíglerová J, Kuncová J, Nalos L, Kubíková T, Liška V, Holubová M, Lysák D, Králíčková M, Vištejnová L, Štengl M. Beneficial effects of mesenchymal stem cells on adult porcine cardiomyocytes in non-contact co-culture. Physiol Res. 2018 Dec 31;67(Supplementum 4):S619-S631

Dejmek J, Kohoutová M, Kripnerová M, Čedíková M, Tůma Z, Babuška V, Bolek L, Kuncová J. Repeated exposure to hyperbaric hyperoxia affects mitochondrial functions of the lung fibroblasts. Physiol Res. 2018 Dec 31;67(Supplementum 4):S633-S643

Hlavac V, Kovacova M, Elsnerova K, Brynychova V, Kozevnikovova R, Raus K, Kopeckova K, Mestakova S, Vrana D, Gatek J, Ostasov P, Vaclavikova R, Soucek P. Use of Germline Genetic variability for prediction of chemoresistance and prognosis of breast cancer patients. Cancers (Basel). 2018 Dec 12;10(12). pii:E511. doi: 10.3390/cancers10120511. PubMed PMID: 30545124

Rotolo A, Caputo VS, Holubova M, Baxan N, Dubois O, Chaudhry MS, Xiao X, Goudevenou K, Pitcher DS, Petevi K, Kachramanoglou C, Iles S, Naresh K, Maher J, Karadimitris A. Enhanced anti-lymphoma activity of car19-inkt cells underpinned by dual CD19 and CD1d targeting. Cancer Cell. 2018 Oct 8;34(4):596-610. PMID: 30300581

Thiele JA, Hosek P, Kralovcova E, Ostasov P, Liska V, Bruha J, Vycital O, Rosendorf J, Opattova A, Horak J, Kralickova M, Vodicka P, Pitule P. lncRNAs in non-malignant tissue have prognostic value in colorectal cancer. Int J Mol Sci. 2018 Sep 8;19(9). pii: E2672. PubMed PMID: 30205577

Polívka J Jr, Pešta M, Pitule P, Hes O, Holubec L, Polívka J, Kubíková T, Tonar Z. IDH1 mutation is associated with lower expression of VEGF but not microvessel formation in glioblastoma multiforme. Oncotarget. 2018 Feb 20;9(23):16462-16476. PMID: 29662659

Fikar P, Georgiev V, Lissorgues G, Holubova M, Lysak D, Georgiev D. 2DEP cytometry: distributed dielectrophoretic cytometry for live cell dielectric signature measurement on population level. BIOMED MICRODEVICES. 2018 Jan 8;20(1):12


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