Stem cells represent a promising approach in a treatment of many severe diseases. One of the biggest challenges is the renewal of nervous system or replacement of life-essential organs. At Biomedical Center, we focus on the research of therapeutic potential of stem cells in liver regeneration, reparation of kidney and heart function in sepsis, in the treatment of neurodegenerative disorders or in the development of bone and joint scaffolds. We aim to evaluate not only the real therapeutic potential of stem cells, but also the molecular, biological and genetic mechanisms of their action.