Identifying novel susceptibility genes for colorectal cancer risk from a transcriptome-wide association study of 125,478 subjects

Team of Laboratory of Cancer Treatment and Tissue Regeneration participates on research of GECCO (The Genetics and Epidemiology of Colorecal Cancer Consortium) in Seattle, USA.

The new outcome appeared in last days. Scientific article: „Identifying novel susceptibility genes for colorectal cancer risk from a transcriptome-wide association study of 125,478 subjects“ is published in Gastroenterology (IF 17.373, Q1) and reveals that five genes in four novel loci are associated with CRC risk in individuals of European descent, along with an additional nine genes in known GWAS loci that have not been previously reported. Identification of CRC risk loci and susceptibility genes can help identify individuals at high risk. These findings have significant implications for genetic screening.

More information find here.

MUDr. Ludmila Vodičková, CSc.

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Charles University
Faculty of Medicine in Pilsen
Biomedical Center

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